Currently, there is only one predefined keyboard layout - QWERTY. 
For example, when the culture is:

• French we should apply the AZERTY layout
• German we should apply the QWERTZ layout
  
  

As a workaround, I have modified and saved the AZERTY and QWERTZ keyboard layouts into XML files. You can use the LoadLayout method of RadVirtualKeyboard to load them.

this.radVirtualKeyboard1.LoadLayout(@"..\..\Layouts\azerty.xml");
//this.radVirtualKeyboard1.LoadLayout(@"..\..\Layouts\qwertz.xml");