Just to report a little typo in RadListViewElement:

Protected Overrides Sub OnCurrecntItemChanged(args As ListViewItemEventArgs)

Thanks.

This problem is even reproducible in our Demo application >> Virtual Grid >> Web service example. You will notice that when you scroll to the bottom, the waiting indicator is not being animated when the DPI scaling is higher than 100%.

If you apply the same gif file in a PictureBox it gets animated when using 150% DPI scaling.

Please refer to the attached sample project and follow the steps illustrated in the gif file.

Note: if the vertical  scrollbar is visible, the editor is activated as expected. 

Workaround:

Me.RadListView1.ItemSize = New Size(200, 30)