Please refer to the following code snippet and follow the steps in the attached gif file:
Dim dt As New DataTable
dt.Columns.Add("Id", GetType(Integer))
dt.Columns.Add("Name", GetType(String))
For index = 1 To 10
dt.Rows.Add(index, "Data" & index & Guid.NewGuid().ToString())
Next
Me.RadMultiColumnComboBox1.DataSource = dt
Me.RadMultiColumnComboBox1.DisplayMember = "Name"
Me.RadMultiColumnComboBox1.ValueMember = "Id"
Me.RadMultiColumnComboBox1.AutoSizeDropDownToBestFit = True
Workaround:
AddHandler Me.RadMultiColumnComboBox1.DropDownOpened, AddressOf RadMultiColumnComboBox_DropDownOpened
Private Sub RadMultiColumnComboBox_DropDownOpened(sender As Object, e As EventArgs)
Me.RadMultiColumnComboBox1.EditorControl.HorizontalScrollState = ScrollState.AutoHide
End Sub