The issue only reproduces on Windows 10( 1806). Check the attached video showing the result: Workaround: Handle the CommandExecuting event this way private void RadRichTextEditor1_CommandExecuting(object sender, Telerik.WinForms.Documents.RichTextBoxCommands.CommandExecutingEventArgs e) { if (e.Command is ChangeFontFamilyCommand && e.CommandParameter.ToString() == "") { e.Cancel = true; } }