Hi John,

RadGridView will not update the database and this behavior is by design. Once you edit a record in the control, the grid will update the data bound object. From that moment it is up to you, depending on your actual scenario and chosen data provider to connect to the database and update it. You can check the following documentation articles providing examples with EntityFramework and ADO.NET:
   https://docs.telerik.com/devtools/winforms/gridview/populating-with-data/binding-to-entityframework-using-database-first-approach
   https://docs.telerik.com/devtools/winforms/gridview/populating-with-data/updating-the-database-with-ado.net

I hope this will help.

Regards