How to reproduce: set the Size property of the form in the designer of Visual Studio, pay attention to the serialized ClientSize value. Run the form and check the ClientSize, it has increased

Workaround: 
public partial class Form2 : RadForm
{
    public Form2()
    {
        InitializeComponent();
        Padding p = TelerikDpiHelper.ScalePadding(this.FormBehavior.ClientMargin, new SizeF(1f / this.RootElement.DpiScaleFactor.Width, 1f / this.RootElement.DpiScaleFactor.Height));
        this.MaximumSize = new Size(this.Size.Width - p.Horizontal, this.Size.Height - p.Vertical- this.FormBehavior.ClientMargin.Bottom + this.FormElement.TitleBar.Size.Height);
    }

    protected override void OnShown(EventArgs e)
    {
        base.OnShown(e);

        this.MaximumSize = new Size(0, 0);
    }
}