Please refer to the attached sample project and follow the steps: If you execute my code sample and try this sequence, you will see my problem: 1- start the application 2- select "test1" on the grid => you see "fonction XX of test1" in the treeview (that's correct) 3- select "test2" on the grid => you see "fonction XX of test2" in the treeview (that's correct) 4- expand all nodes in the treeview 5- uncheck "fonction 31 of test2" in the treeview 6- select "test1" on the grid => you have the error message. On the grid, we have "test1" selected and on the treeview we have "test2". Note that the problem appears only when checking a node in the treeview on a second level. If you follow this procedure, you will have no problem : 1- restart the application 2- select "test1" on the grid => you see "fonction XX of test1" in the treeview (that's correct) 3- select "test2" on the grid => you see "fonction XX of test2" in the treeview (that's correct) 4- uncheck "fonction 30 of test2" in the treeview 5- select "test1" on the grid => you will have no error. On the grid, we have "test1" selected and on the treeview we have "test1". 6- select "test2" on the grid => you will have no error. On the grid, we have "test2" selected and on the treeview we have "test2" with "fonction 30 of test2" unchecked. Workaround: in order to synchronize the current row in RadGridView is to change the RadTreeView.DataSource in the RadGridView.CurrentRowChanged event.