To reproduce: - Add 100000 rows to the grid. - Filter the grid so there are no rows. - Call the BestFitColumns method: radGridView1.MasterTemplate.BestFitColumns(Telerik.WinControls.UI.BestFitColumnMode.DisplayedCells) Workaround: If gridview.MasterTemplate.DataView.Count > 0 Then gridview.MasterTemplate.BestFitColumns() End If