Please refer to the attached sample project and follow the steps illustrated on the attached gif file. Workaround: subscribe to the CellBeginEdit event and focus the grid: public partial class UserControl1 : UserControl { public UserControl1() { InitializeComponent(); this.radGridView1.CellBeginEdit += radGridView1_CellBeginEdit; } private void radGridView1_CellBeginEdit(object sender, GridViewCellCancelEventArgs e) { this.radGridView1.Focus(); } }