To reproduce: - Add three line series and only set their point size. - At runtime remove the second series. - The points color is not updated corectly. Workaround - Set colors in code like this: lineSerie1.BorderColor = Color.Red; lineSerie1.BackColor = Color.Red; lineSerie2.BackColor = Color.Green; lineSerie2.BorderColor = Color.Green; lineSerie3.BackColor = Color.Blue; lineSerie3.BorderColor = Color.Blue;