To reproduce: 
1. Add RadChartView with drill down and two RadCheckBox on the form
2. Subscribe to the ToggleStateChanged event of RadCheckBox and set the IsVisible property to true/false 
3. In handler of DrillDown event set the series`s IsVisible property to be equal to checkbox`s Checked property
4. In few cases the series are not visible when changing the IsVisible property and view. 

Unfortunately due to the nature of the issue we cannot provide a workaround for it.