To reproduce: private void radButton1_Click(object sender, EventArgs e) { this.nwindDataSet.Products.Clear(); this.productsTableAdapter.Fill(this.nwindDataSet.Products); radListView1.DataSource = this.nwindDataSet.Products; } Workaround: private void radButton1_Click(object sender, EventArgs e) { this.nwindDataSet.Products.Clear(); this.productsTableAdapter.Fill(this.nwindDataSet.Products); radListView1.DataSource = null; radListView1.DataSource = this.nwindDataSet.Products; }