1. Use the following code snippet: public Form1() { InitializeComponent(); this.radGridView1.MasterTemplate.AutoSizeColumnsMode = Telerik.WinControls.UI.GridViewAutoSizeColumnsMode.Fill; this.radGridView1.MasterTemplate.EnableAlternatingRowColor = true; this.radGridView1.MasterTemplate.EnableFiltering = true; this.radGridView1.MasterTemplate.MultiSelect = true; for (int i = 0; i < 3; i++) { this.radGridView1.Columns.Add("Col"+i); } radGridView1.Rows.Add("test1", "test1", "test1"); radGridView1.Rows.Add("test2", "test2", "test2"); radGridView1.Rows.Add("test3", "test3", "test3"); radGridView1.Rows.Add("test4", "test4", "test4"); radGridView1.Rows.Add("test5", "test5", "test5"); } 2. Quickly click around the cells a few times, making sure to drag your mouse a bit to select a few rows on some of the clicks. Then quickly click the filter. (sometimes it takes a few tries) Workaround: use custom GridFilterRowBehavior BaseGridBehavior gridBehavior = radGridView1.GridBehavior as BaseGridBehavior; gridBehavior.UnregisterBehavior(typeof(GridViewFilteringRowInfo)); gridBehavior.RegisterBehavior(typeof(GridViewFilteringRowInfo), new CustomGridFilterRowBehavior()); public class CustomGridFilterRowBehavior : GridFilterRowBehavior { protected override bool ProcessMouseSelection(Point mousePosition, GridCellElement currentCell) { return false; } }