To reproduce: 1. Add a RadTreeView with several nodes 2. Subscribe to the EditorRequired event and specify the editor to TreeViewTextBoxEditor where its Multiline property is set to true. 3. Select a node and press F2. The editor is activated. However, when you enter some text and press Ctrl+Enter, the editor is closed. The expected behavior is that a new line is inserted. Workaround: private void radTreeView1_EditorRequired(object sender, TreeNodeEditorRequiredEventArgs e) { CustomTreeViewTextBoxEditor editor = new CustomTreeViewTextBoxEditor(); editor.Multiline = true; e.Editor = editor; } public class CustomTreeViewTextBoxEditor : TreeViewTextBoxEditor { protected override void OnKeyDown(KeyEventArgs e) { if (e.KeyCode == Keys.Enter && e.Modifiers == Keys.Control && this.Multiline) { return; } base.OnKeyDown(e); } }