To reproduce:
- Create blank WinForms RadForm Application.
- Set WindowState property to Maximized.
- Add RadGroupBox to the form. Set equal space on all sides.
- Anchor the group box to all sides.
- Launch application - spacing around outside of group box is incorrect.
-  Restore form to normal size - spacing around group box is incorrect.

Workaround:
radGroupBox1.Dock = DockStyle.Fill;
radGroupBox1.GroupBoxElement.Margin = new Padding(20);