Use the following code snippet: public Form1() { InitializeComponent(); GridViewDecimalColumn decimalColumn = new GridViewDecimalColumn("Id"); radGridView1.MasterTemplate.Columns.Add(decimalColumn); GridViewTextBoxColumn textBoxColumn = new GridViewTextBoxColumn("Name"); radGridView1.MasterTemplate.Columns.Add(textBoxColumn); GridViewDateTimeColumn dateTimeColumn = new GridViewDateTimeColumn("CreatedOn"); radGridView1.MasterTemplate.Columns.Add(dateTimeColumn); radGridView1.AutoSizeColumnsMode = GridViewAutoSizeColumnsMode.Fill; for (int i = 0; i < 10; i++) { radGridView1.Rows.Add(i, "Name" + i, DateTime.Now.AddDays(i)); } radGridView1.ClipboardPasteMode = GridViewClipboardPasteMode.Disable; } If you copy a cell content and try to paste it to another cell of the same column, the content is pasted successfully, although the ClipboardPasteMode property is set to Disable.