To reproduce: - Add RadWizard to a form. - Set the AcceptButton property like this: this.AcceptButton = this.radWizard1.NextButton; - You will notice that nothing happens when the enter key is pressed. Workaround: - Use the following PreviewKeyDown event handler: void radWizard1_PreviewKeyDown(object sender, PreviewKeyDownEventArgs e) { if (e.KeyCode == Keys.Enter) { this.radWizard1.NextButton.PerformClick(); } }