To reproduce: - Add RadDateTimePicker to a form and set its ReadOnly property to true. - Paste a valid value using the Ctrl+V key combination. Workaround: - Disable the corresponding key combination in the KeyDown event: void radDateTimePicker1_KeyDown(object sender, KeyEventArgs e) { if (e.Control && e.KeyCode == Keys.V) { e.SuppressKeyPress = true; } }