When RadMessageBox has not owner and it is using in form that has TopMost = true throws exception after first call of RadMessageBox.Show() Steps to reproduce: 1.Create From with TopMost = true 2. Add button and insert the following code in press event: RadMessageBox.Show("Text"); 3.Run application and press the button two times. Workaround after each show of RadMessageBox add this code snippet: RadMessageBox.Instance.Dispose();