When the scale and layout setting of the machine is different than 100% the keyboard navigation does not work properly. The issue occurs with different scales on each machine. For example, on some machines, it could work with all scales, but on others, it may not work with a scale of 125% or 175%, even if this is the recommended value.
Note, that you may need to test with different scales to manage to replicate the issue.
The navigation does not work. The cell selection does not work or goes to a wrong cell.
The Spreadsheet navigation should work with all screen scales.