InvalidCastException is thrown when the DropIndicatorThickness property of the GridViewHeaderCell is set. Or whenever the DropIndicatorBrush property is accessed. This happens when using the Windows 7 theme. Also, the EnableColumnVirtualization property should be set to False.

System.InvalidCastException: 'Unable to cast object of type 'System.Windows.Media.LinearGradientBrush' to type 'System.Windows.Media.SolidColorBrush'.'

To work this around, you can use an implicit style targeting the GridViewHeaderCell in order to set its DropIndicatorBrush to a SolidColorBrush value.

 <telerik:RadGridView.Resources>
     <Style TargetType="telerik:GridViewHeaderCell">
         <Setter Property="DropIndicatorBrush" Value="White" />
         <Setter Property="DropIndicatorThickness" Value="10" />
     </Style>
 </telerik:RadGridView.Resources>