In the Office2019 theme, the RadGridView's ScrollBar elements should have transparent background by design. This is the track's background shown behind the thumb element that allows drag-to-scroll. Currently, the ScrollBars have a gray background.
To work this around, you can define an implicit Style in the App.xaml that targets the GridViewScrollViewer control. Then, set its Background property.
<Application.Resources>
<ResourceDictionary>
<ResourceDictionary.MergedDictionaries>
<ResourceDictionary Source="/Telerik.Windows.Themes.Office2019;component/Themes/System.Windows.xaml"/>
<ResourceDictionary Source="/Telerik.Windows.Themes.Office2019;component/Themes/Telerik.Windows.Controls.xaml"/>
<ResourceDictionary Source="/Telerik.Windows.Themes.Office2019;component/Themes/Telerik.Windows.Controls.Input.xaml"/>
<ResourceDictionary Source="/Telerik.Windows.Themes.Office2019;component/Themes/Telerik.Windows.Controls.GridView.xaml"/>
</ResourceDictionary.MergedDictionaries>
<Style TargetType="telerik:GridViewScrollViewer" BasedOn="{StaticResource GridViewScrollViewerStyle}">
<Setter Property="Background" Value="Transparent"/>
</Style>
</ResourceDictionary>
</Application.Resources>