This is reproducible only if the ribbon window chrome is enabled (IsWindowsThemeEnabled=False). You can resolve this by registering an input binding for the Alt+Space key gesture and attaching it to the Telerik.Windows.Controls.RibbonView.Shell.SystemCommands.ShowSystemMenuCommand RoutedUICommand. static MainWindow() { var keyBinding = new KeyBinding(Telerik.Windows.Controls.RibbonView.Shell.SystemCommands.ShowSystemMenuCommand, new KeyGesture(Key.Space, ModifierKeys.Alt)); CommandManager.RegisterClassInputBinding(typeof(RadRibbonWindow), keyBinding); RadRibbonWindow.IsWindowsThemeEnabled = false; }