In R2 2019 there is a regression bug in RadTabControl.Clicking with mouse middle button over a tab removes it from the Items collection.
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Workaround: In R2 2019 or for particular items, user can handle PreviewMouseDown event of the RadTabItem and if the pressed button is middle - handle the event.
private void RadTabItem_PreviewMouseDown(object sender, MouseButtonEventArgs e)
{
if (e.ChangedButton == MouseButton.Middle)
{
e.Handled = true;
}
}