When modifying Interactive Forms TextBoxField's value the entered changes are preserved after is clicked out of the TextBoxField's editing area. However the changes are not applied when the click is performed on the save button.

As possible workaround you can raise a MouseLeftButtonDown event on the RadPdfViewer and after this execute the SaveAsCommand. For example:

private void SaveButton_Click(object sender, RoutedEventArgs e)
{
    MouseButtonEventArgs mouseEventArgs = new MouseButtonEventArgs(Mouse.PrimaryDevice, 0, MouseButton.Left)
    {
        RoutedEvent = FrameworkElement.MouseLeftButtonDownEvent
    };
 
    ((FrameworkElement)this.pdfViewer.FixedDocumentPresenter).RaiseEvent(mouseEventArgs);
    this.pdfViewer.CommandDescriptors.SaveAsCommandDescriptor.Command.Execute(null);
}