The popup is no properly sized when you have two or more monitors with different resolutions. This is replicable also if the DPI is higher than 100%.

To work this around you can create a custom ribbonview, get the content presenter of the popup and manually set its Width. Here is an example in code:

public class CustomRibbonView : RadRibbonView
{
	private ContentPresenter selectedTabContentPopup;

	public override void OnApplyTemplate()
	{
		base.OnApplyTemplate();
		this.selectedTabContentPopup = this.GetTemplateChild("SelectedTabContentPopup") as ContentPresenter;
	}

	protected override void OnMinimizedPopupStateChanged(RadRoutedEventArgs e)
	{   
		base.OnMinimizedPopupStateChanged(e);
		if (this.IsMinimizedPopupOpen)
		{
			this.selectedTabContentPopup.Width = this.ActualWidth;
		}
	}
}