To replicate the problem:
Clicking on the Edit button fires the RowClick event of the Grid instead of Edit/Save/Cancel.
 
	
		<script type="text/javascript">    var old = Telerik.Web.UI.GridSelection.prototype._click    Telerik.Web.UI.GridSelection.prototype._click = function(e)     {        var el = (e.target)? e.target : e.srcElement;        if ($telerik.isTouchDevice && el.nodeType == 3)        {            el = el.parentNode;        }        if (!el.tagName) return;        // If the span element clicked is a child element of a button, do not raise the row click event        if (el.tagName.toLowerCase() == "span" && el.parentElement.tagName.toLowerCase() == "button") return;        // call the original code        old.call(this, e);    }</script><button type="button" name="RadGrid1$ctl00$ctl04$EditButton" value="Edit" onclick="javascript:__doPostBack('RadGrid1$ctl00$ctl04$EditButton','')" id="RadGrid1_ctl00_ctl04_EditButton" title="Edit" class="t-button rgActionButton rgEdit">    <span class="t-font-icon rgIcon rgEditIcon"></span></button>