Workaround - placing the following script after the ScriptManager: <script type="text/javascript"> Telerik.Web.UI.RadGantt.prototype.postback = function (args) { var postbackFunction = this.get_postBackReference().replace("arguments", Sys.Serialization.JavaScriptSerializer.serialize(args).replace(/\\/g, "\\\\").replace(/'/g, "\\'")); eval(postbackFunction); } </script>