A workaround is to disable the embedded jQuery and use an older version (for example, 1.11.1 which is the previous version the suite used): https://docs.telerik.com/devtools/aspnet-ajax/controls/scriptmanager/disabling-the-embedded-jquery Repro steps: - Put a searchbox on the page with some data source - Hook its postback handler, OnSearch - search something in it, select the item to postback expected: search fired actual: JS error in FF <telerik:RadSearchBox RenderMode="Lightweight" runat="server" ID="RadSearchBox1" DataTextField="Name" DataValueField="id" OnSearch="RadSearchBox1_Search"> </telerik:RadSearchBox> protected void Page_Load(object sender, EventArgs e) { RadSearchBox1.DataSource = GetData(); RadSearchBox1.DataBind(); } protected DataTable GetData() { DataTable tbl = new DataTable(); tbl.Columns.Add(new DataColumn("id", typeof(decimal))); tbl.Columns.Add(new DataColumn("Name", typeof(string))); tbl.Columns.Add(new DataColumn("Reason", typeof(string))); tbl.Columns.Add(new DataColumn("someField", typeof(decimal))); tbl.Columns.Add(new DataColumn("anotherField", typeof(string))); tbl.Rows.Add(new object[] { 1, "one", "fi\\nrst", 2, "5" }); tbl.Rows.Add(new object[] { 2, "two", @"se\ncond", 3, null/*SIMULATE EMPTY VALUE*/ }); tbl.Rows.Add(new object[] { 3, "three", "third", 4, "5" }); tbl.Rows.Add(new object[] { 4, "four", "fourth", 5, "5" }); return tbl; } protected void RadSearchBox1_Search(object sender, SearchBoxEventArgs e) { Response.Write(DateTime.Now.ToString()); }