Changing the render mode of the Editor Dynamically on the server-side leads to a JavaScript error: Uncaught TypeError: Cannot read property 'render' of null at Telerik.Web.UI.Editor.Modules.RadEditorNodeInspector.render The issue is introduced in 2016 R3. Steps to reproduce: Run the following configuration: <telerik:RadEditor ID="RadEditor1" runat="server"></telerik:RadEditor> CS: protected void Page_Load(object sender, EventArgs e) { RadEditor1.RenderMode = Telerik.Web.UI.RenderMode.Mobile; }