The issue is reproducible when you add a CSS class, responsible for styling the scrollbars, too lately and can also be reproduced on a page that contains no Telerik UI for ASP.NET AJAX controls: <html xmlns="http://www.w3.org/1999/xhtml"> <head runat="server"> <title></title> <style> .RadForm.rfdScrollBars.RadForm_WebBlue div::-webkit-scrollbar, .RadForm.rfdScrollBars.RadForm_WebBlue div::-webkit-scrollbar-thumb:vertical, .RadForm.rfdScrollBars.RadForm_WebBlue div::-webkit-scrollbar-thumb:horizontal { background-color: red !important; /* choose your color */ } </style> </head> <body> <form id="form1" runat="server"> <telerik:RadScriptManager ID="RadScriptManager1" runat="server"></telerik:RadScriptManager> <script> setTimeout(function () { Sys.UI.DomElement.addCssClass(document.documentElement, "RadForm RadForm_WebBlue rfdScrollBars"); }, 10); </script> <div id="testDiv" style="overflow: scroll; height: 200px; width: 300px"> <table> <tr style="height: 500px;"> <td></td> </tr> </table> </div> </form> </body> </html> If you remove the timeout, however, the issue will be gone: <script> // setTimeout(function () { Sys.UI.DomElement.addCssClass(document.documentElement, "RadForm RadForm_WebBlue rfdScrollBars"); // }, 10); </script> Possible workarounds for scenarios when the RadFormDecorator control is involved: 1) Remove the scorllbars styling by setting the ControlsToSkip property to "Scrollbars". <telerik:RadFormDecorator ID="RadFormDecorator1" runat="server" DecoratedControls="All" ControlsToSkip="Scrollbars" /> 2) Use the following JavaScript workaround: <form id="form1" runat="server"> <telerik:RadScriptManager ID="RadScriptManager1" runat="server"></telerik:RadScriptManager> <telerik:RadSkinManager ID="RadSkinManager1" runat="server" Skin="Glow"></telerik:RadSkinManager> <telerik:RadFormDecorator ID="RadFormDecorator1" runat="server" DecoratedControls="All" ControlsToSkip="Scrollbars" /> <script> //JavaScript workaround: Telerik.Web.UI.RadFormDecorator.removeGlobalClassesToRootElement = function (rootElement) { rootElement.className = rootElement.className.replace(/rfdRtl|RadForm_\w+|rfdButton|rfdZone|rfdLabel|rfdHeading|rfdTextbox|rfdTextarea|rfdFieldset|rfdRadio|rfdCheckbox|rfdGrids/g, "").trim(); }; Sys.UI.DomElement.addCssClass(document.documentElement, "RadForm RadForm_<%=RadSkinManager.GetCurrent(this.Page).Skin%> rfdScrollBars"); </script> <div id="testDiv" style="overflow: scroll; height: 200px; width: 300px"> <table> <tr style="height: 500px;"> <td></td> </tr> </table> </div> </form>