For the time being you can capture the keypress event of the submitting button and cancel it only if the Enter key is pressed. For example: <telerik:RadCodeBlock ID="RadCodeBlock1" runat="server"> <script> Sys.Application.add_load(function () { var decoratedButton = Telerik.Web.UI.RadFormDecorator.getDecoratedElement($get("<%=SearchButton.ClientID%>")); cancelKeyPress(decoratedButton); }); function cancelKeyPress() { Array.forEach(arguments, function (element) { $addHandler(element, "keypress", function (event) { if (event.charCode == 13) $telerik.cancelRawEvent(event.rawEvent); }); }); } </script> </telerik:RadCodeBlock> <telerik:RadFormDecorator ID="RadFormDecorator1" runat="server" DecoratedControls="All" /> <asp:Panel ID="SearchPanel" runat="server" DefaultButton="SearchButton"> <telerik:RadTextBox FocusedStyle-CssClass="textfocused" TabIndex="1" HoveredStyle-CssClass="texthover" ID="SearchText" runat="server" Width="200px" Height="22px" /> <asp:Button ID="SearchButton" runat="server" Text="Search" TabIndex="3" OnClick="SearchButton_Click" OnClientClick="alert(1);return true;" /> </asp:Panel>