Due to initial invalid content the Editor's ConvertToXhtml filter throws a JS error that breaks the further initialization of the control. A possible resolution is incorporating the following sample code: <telerik:RadEditor runat="server" ID="RadEditor1" OnClientLoad="OnClientLoad"> </telerik:RadEditor> <script type="text/javascript"> Telerik.Web.UI.Editor.NestedElementsFix.prototype._getLastInvalidWrapper = function (node) { var parent = node; while (parent.parentNode && this._shouldUnwrapNode(parent.parentNode)) { parent = parent.parentNode; } return parent == node ? null : parent; } function OnClientLoad(editor, args) { editor.set_html(editor.get_html(true)); } </script>