The shortcut TAB key provides correct behavior only for IE ( entities are added). UNder Firefox and Chrome the behavior is incorrect and not expected. In FF - nothing is added to the content, moves the focus to the next HTML element. In Chrome - a SPAN element is inserted. A possible resolutions replacing the added shortcut for TAB key with the InsertTab command: <telerik:RadEditor ID="RadEditor1" runat="server" OnClientLoad="OnClientLoad"> </telerik:RadEditor> <script type="text/javascript"> function OnClientLoad(editor, args) { var shortcutManager = editor.get_shortCutManager(); if (shortcutManager.findShortCutByName("InsertTabMozilla")) { shortcutManager.removeShortCut("InsertTabMozilla"); editor.addShortCut("InsertTab", "TAB"); } } </script>