If an image occurs after some text and it is floated, then in Chrome the image properties dialog will have empty field values and no updates can be made to the image.

Use the HTML below on the demo page and the issue can be seen.

http://demos.telerik.com/aspnet-ajax/editor/examples/overview/defaultcs.aspx

Sample content
This is some text<img alt="" style="float: right;" src="/aspnet-ajax/Editor/Img/UserDir/Marketing/telerik_125x125_asp.gif" />