If a TabStrip with two editors is configured, the editor in the first tab is working correctly, but if the second is shown - its toolbar is not working as expected. Possible resolution is to insert a meta tag in the head element of the main page, which sets the rendering engine of IE10: <meta http-equiv="x-ua-compatible" content="IE=10" /> Another possible resolution is to call the onParentNodeChanged() method after the tab is selected: <telerik:RadTabStrip ID="RadTabStrip1" runat="server" SelectedIndex="0" MultiPageID="RadMultiPage1" OnClientTabSelected="OnClientTabSelected"> <Tabs> <telerik:RadTab runat="server" PageViewID="RadPageView1" Selected="True" Text="Root RadTab1"> </telerik:RadTab> <telerik:RadTab runat="server" PageViewID="RadPageView2" Text="Root RadTab2"> </telerik:RadTab> </Tabs> </telerik:RadTabStrip> <telerik:RadMultiPage ID="RadMultiPage1" runat="server"> <telerik:RadPageView ID="RadPageView1" runat="server" Width="100%" Selected="True"> <telerik:RadEditor ID="RadEditor1" runat="server"> <Content> Content Page 1 </Content> <TrackChangesSettings CanAcceptTrackChanges="False" /> </telerik:RadEditor> </telerik:RadPageView> <telerik:RadPageView ID="RadPageView2" runat="server" Width="100%"> <telerik:RadEditor ID="RadEditor2" runat="server"> <Content> Content Page 2 </Content> <TrackChangesSettings CanAcceptTrackChanges="False" /> </telerik:RadEditor> </telerik:RadPageView> </telerik:RadMultiPage> <script type="text/javascript"> function OnClientTabSelected(sender, args) { var tabIndex = args.get_tab().get_index(); if (tabIndex === 1) { var editor = $find("<%= RadEditor2.ClientID %>"); editor.onParentNodeChanged(); } } </script>