The following mouse events are not triggered with IE, they work fine with Firefox and : MouseEvent mouseClickEvent = newMouseEvent("click"); mouseClickEvent.CanBubble = true; mouseClickEvent.IsCancelable = true; MouseEvent mouseDownEvent = newMouseEvent("mousedown"); mouseDownEvent.CanBubble = true; mouseDownEvent.IsCancelable = true; MouseEvent mouseUpEvent = newMouseEvent("mouseup"); mouseDownEvent.CanBubble = true; mouseDownEvent.IsCancelable = true; anchor.InvokeEvent(mouseDownEvent); anchor.InvokeEvent(mouseClickEvent); anchor.InvokeEvent(mouseUpEvent); Steps to reproduce: Execute the project attached.