- Create a new project containing RadGridView
- Build hierarchy with large text data in cells
- Set the AutoSizeRows property to true and AutoSizeColumnMode to Fill
- Run the project, scroll down and try to click on a cell

To reproduce:

Update the data source directly and check the OldItems array.

To reproduce:
- Use a column with numbers stored as strings.
- Set the data type to decimal
- The columns should be sorted according to the number value not alphabetically.

Workaround:
var col = new GridViewTextBoxColumn();
col.DataTypeConverter = new DecimalConverter();
col.FieldName = "Dosage";
col.UseDataTypeConverterWhenSorting = true;
col.DataType = typeof(decimal);
radGridView1.Columns.Add(col);

public class DecimalConverter : TypeConverter
{
    public override bool CanConvertTo(ITypeDescriptorContext context, Type destination_type)
    {
        
        if (destination_type == typeof(decimal))
        {
            return true;
        }

        return base.CanConvertTo(context, destination_type);
    }
    public override object ConvertTo(ITypeDescriptorContext context, CultureInfo culture, object value, Type destination_type)
    {
        if (destination_type == typeof(decimal))
        {
            return decimal.Parse(value.ToString());
        }

        return base.ConvertTo(context, culture, value, destination_type);
    }
}

"High Performance with RadGridView and Virtual Mode including Filtering, Sorting and Grouping" example is not working for RadGridView Q3 2015. When I click on the Column header for sorting ( same thing for grouping and filtering)  and I m getting exception "Sorting operation is not supported in VirtualMode.".  Same sample is working for Q3 2014. Following is the URL for the sample 
http://www.telerik.com/support/kb/winforms/gridview/details/high-performance-with-radgridview-and-virtual-mode-including-filtering-sorting-and-grouping

how can i insert , update or delete? i tried after choosing the data source , it shows the data correctly but when i edit or add a new item the database is not affected (allow edit,delete and add row are set to true)

Use attached to reproduce.

With versions prior 2015.3.930 the results are different.

I have a GridView (Winforms v. 2017.3.1017.40, same problem with 2017.2.502.40) configured as on the attached screenshot (made some groups, made a search, and used the "excel-like" filter on a column to uncheck some values).

Then I try to click on some column headers to sort the grid.
After a few clicks, I get this error :
InvalidOperationException: La collection a été modifiée ; l'opération d'énumération peut ne pas s'exécuter.

I got different stacktrace with the same error :
InvalidOperationException: La collection a été modifiée ; l'opération d'énumération peut ne pas s'exécuter.
   at System.ThrowHelper.ThrowInvalidOperationException(ExceptionResource resource)
   at System.Collections.Generic.List`1.Enumerator.MoveNextRare()
   at System.Collections.Generic.List`1.Enumerator.MoveNext()
   at Telerik.WinControls.UI.DataGroup.<GetEnumerator>d__0.MoveNext()
   at Telerik.WinControls.UI.GridViewGroupRowInfo.get_ChildRows()
   at Telerik.WinControls.UI.GridViewRowInfo.HasChildRows()
   at Telerik.WinControls.UI.PrintGridTraverser.CanStepInHierarchy()
   at Telerik.WinControls.UI.GridTraverser.StepInHierarchy()
   at Telerik.WinControls.UI.GridTraverser.MoveNextCore()
   at Telerik.WinControls.UI.GridTraverser.MoveNext()
   at Telerik.WinControls.UI.GridViewSearchRowInfo.worker_DoWork(Object sender, DoWorkEventArgs e)
   at System.ComponentModel.BackgroundWorker.OnDoWork(DoWorkEventArgs e)
   at System.ComponentModel.BackgroundWorker.WorkerThreadStart(Object argument)

-----

InvalidOperationException: Failed to compare two elements in the array. ---> NullReferenceException: Object reference not set to an instance of an object.
   at Telerik.WinControls.UI.GridViewRowInfoComparer.CompareRows(GridViewRowInfo x, GridViewRowInfo y, SortDescriptorCollection context)
   at System.Collections.Generic.ArraySortHelper`1.InternalBinarySearch(T[] array, Int32 index, Int32 length, T value, IComparer`1 comparer)
   at System.Collections.Generic.ArraySortHelper`1.BinarySearch(T[] array, Int32 index, Int32 length, T value, IComparer`1 comparer)


   --- End of inner exception stack trace ---
   at System.Collections.Generic.ArraySortHelper`1.BinarySearch(T[] array, Int32 index, Int32 length, T value, IComparer`1 comparer)
   at System.Collections.Generic.List`1.BinarySearch(Int32 index, Int32 count, T item, IComparer`1 comparer)
   at Telerik.Collections.Generic.HybridIndex`1.PerformWithQuickSort()
   at Telerik.Collections.Generic.HybridIndex`1.get_Items()
   at Telerik.Collections.Generic.Index`1.GetEnumerator()
   at Telerik.WinControls.Data.GroupBuilder`1.Perform(IReadOnlyCollection`1 items, Int32 level, Group`1 parent)
   at Telerik.WinControls.Data.GroupBuilder`1.get_Groups()
   at Telerik.WinControls.UI.GridViewInfo.Refresh()
   at Telerik.WinControls.UI.GridViewInfo.get_ChildRows()
   at Telerik.WinControls.UI.ViewInfoTraverser.SetCollectionForStage(Boolean initializeCollection)
   at Telerik.WinControls.UI.ViewInfoTraverser.ChangeCollectionForward()
   at Telerik.WinControls.UI.ViewInfoTraverser.MoveNextCore()
   at Telerik.WinControls.UI.ViewInfoTraverser.MoveNext()
   at Telerik.WinControls.UI.GridTraverser.MoveNextCore()
   at Telerik.WinControls.UI.GridTraverser.MoveNext()
   at Telerik.WinControls.UI.BaseGridNavigator.NavigateToRow(GridViewRowInfo row, Boolean select)
   at Telerik.WinControls.UI.BaseGridNavigator.ProcessViewChangedEvent(GridViewEvent eventData)
   at Telerik.WinControls.UI.BaseGridNavigator.ProcessEventCore(GridViewEvent eventData)
   at Telerik.WinControls.UI.GridViewEventProcessEntity.ProcessCollection(GridViewEvent gridEvent, PriorityWeakReferenceList list, GridEventProcessMode processMode)
   at Telerik.WinControls.UI.GridViewEventProcessEntity.ProcessEvent(GridViewEvent gridEvent)
   at Telerik.WinControls.UI.GridViewSynchronizationService.NotifyListeners(GridViewEvent gridEvent)
   at Telerik.WinControls.UI.GridViewSynchronizationService.FlushEvents()
   at Telerik.WinControls.UI.GridViewSynchronizationService.DispatchEvent(GridViewEvent gridEvent)
   at Telerik.WinControls.UI.GridViewSynchronizationService.DispatchEvent(GridViewTemplate template, GridViewEvent eventData, Boolean postUI)
   at Telerik.WinControls.UI.GridViewTemplate.DispatchDataViewChangedEvent(Object sender, DataViewChangedEventArgs args)
   at Telerik.WinControls.UI.GridViewTemplate.OnViewChanged(Object sender, DataViewChangedEventArgs e)
   at Telerik.WinControls.UI.MasterGridViewTemplate.OnViewChanged(Object sender, DataViewChangedEventArgs e)
   at Telerik.WinControls.Data.RadDataView`1.RebuildData(Boolean notify)
   at Telerik.WinControls.Data.RadDataView`1.OnNotifyPropertyChanged(PropertyChangedEventArgs e)
   at Telerik.WinControls.Data.RadCollectionView`1.OnNotifyPropertyChanged(String propertyName)
   at Telerik.WinControls.UI.GridViewSortDescriptorCollection.OnCollectionChanged(NotifyCollectionChangedEventArgs args)
   at System.ComponentModel.PropertyChangedEventHandler.Invoke(Object sender, PropertyChangedEventArgs e)
   at Telerik.WinControls.Data.SortDescriptor.set_Direction(ListSortDirection value)
   at Telerik.WinControls.UI.GridViewColumn.Sort(RadSortOrder sortOrder, Boolean multiSortMode)
   at Telerik.WinControls.UI.GridHeaderCellElement.Sort(RadSortOrder sortOrder)
   at Telerik.WinControls.UI.GridHeaderRowBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.UI.BaseGridBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.UI.RadGridView.OnMouseUp(MouseEventArgs e)
   at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)
   at System.Windows.Forms.Control.WndProc(Message& m)
   at Telerik.WinControls.RadControl.WndProc(Message& m)
   at Telerik.WinControls.UI.RadGridView.WndProc(Message& m)
   at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

------

InvalidOperationException: Collection was modified; enumeration operation may not execute.
   at System.ThrowHelper.ThrowInvalidOperationException(ExceptionResource resource)
   at System.Collections.Generic.List`1.Enumerator.MoveNextRare()
   at System.Collections.Generic.List`1.Enumerator.MoveNext()
   at Telerik.WinControls.UI.DataGroup.<GetEnumerator>d__0.MoveNext()
[...]
   at System.Collections.Generic.List`1..ctor(IEnumerable`1 collection)
   at System.Linq.Enumerable.ToList[TSource](IEnumerable`1 source)
   at Alto.Client.Controls.Dispatch.DispatchResources.DeliveryPointFilterManager.get_DeliveryPointsVisible() in d:\Builds\45153\Alto\Alto.Prod\src\Alto\Alto.Client\Controls\Dispatch\DispatchResources\DeliveryPointFilterManager.cs:line 38
   at Alto.Client.Controls.Dispatch.DispatchResources.UcDeliveryPoint.get_Title() in d:\Builds\45153\Alto\Alto.Prod\src\Alto\Alto.Client\Controls\Dispatch\DispatchResources\UcDeliveryPoint.cs:line 1520
   at Alto.Client.Controls.Dispatch.DispatchResources.UcDeliveryPoint.updatePanelTitle() in d:\Builds\45153\Alto\Alto.Prod\src\Alto\Alto.Client\Controls\Dispatch\DispatchResources\UcDeliveryPoint.cs:line 543
   at Alto.Client.Controls.Dispatch.DispatchResources.UcDeliveryPoint.onFilterChanged(Object sender, GridViewCollectionChangedEventArgs e) in d:\Builds\45153\Alto\Alto.Prod\src\Alto\Alto.Client\Controls\Dispatch\DispatchResources\UcDeliveryPoint.cs:line 547
   at Telerik.WinControls.UI.GridViewCollectionChangedEventHandler.Invoke(Object sender, GridViewCollectionChangedEventArgs e)
   at Telerik.WinControls.UI.RadGridView.OnFilterChanged(Object sender, GridViewCollectionChangedEventArgs e)
   at Telerik.WinControls.UI.EventDispatcher.RaiseEvent[T](Object eventKey, Object sender, T args)
   at Telerik.WinControls.UI.GridViewFilterDescriptorCollection.OnCollectionChanged(NotifyCollectionChangedEventArgs args)
   at Telerik.Collections.Generic.NotifyCollection`1.InsertItem(Int32 index, T item)
   at Telerik.WinControls.UI.GridViewFilterDescriptorCollection.InsertItem(Int32 index, FilterDescriptor item)
   at System.Collections.ObjectModel.Collection`1.Add(T item)
   at Telerik.WinControls.UI.GridViewDataColumn.SetFilterDescriptor(FilterDescriptor value)
   at Telerik.WinControls.UI.GridHeaderCellElement.filterPopup_FilterConfirmed(Object sender, EventArgs e)
   at Telerik.WinControls.UI.BaseFilterPopup.OnFilterConfirmed()
   at Telerik.WinControls.UI.RadListFilterPopup.OnButtonOkClick(EventArgs e)
   at Telerik.WinControls.UI.RadListFilterPopup.ButtonOK_Click(Object sender, EventArgs e)
   at Telerik.WinControls.RadElement.OnClick(EventArgs e)
   at Telerik.WinControls.UI.RadButtonItem.OnClick(EventArgs e)
   at Telerik.WinControls.UI.RadButtonElement.OnClick(EventArgs e)
   at Telerik.WinControls.RadElement.DoClick(EventArgs e)
   at Telerik.WinControls.RadElement.RaiseBubbleEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadItem.RaiseBubbleEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadElement.RaiseRoutedEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadElement.RaiseBubbleEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadItem.RaiseBubbleEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadElement.RaiseRoutedEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadElement.DoMouseUp(MouseEventArgs e)
   at Telerik.WinControls.ComponentInputBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.RadControl.OnMouseUp(MouseEventArgs e)
   at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)
   at System.Windows.Forms.Control.WndProc(Message& m)
   at System.Windows.Forms.ScrollableControl.WndProc(Message& m)
   at Telerik.WinControls.RadControl.WndProc(Message& m)
   at Telerik.WinControls.UI.RadPopupControlBase.WndProc(Message& m)
   at System.Windows.Forms.Control.ControlNativeWindow.OnMessage(Message& m)
   at System.Windows.Forms.Control.ControlNativeWindow.WndProc(Message& m)
   at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

----

InvalidOperationException: Collection was modified; enumeration operation may not execute.
   at System.Collections.Generic.List`1.Enumerator.MoveNextRare()
   at Telerik.WinControls.UI.DataGroup.<GetEnumerator>d__0.MoveNext()
   at Telerik.WinControls.Data.GroupBuilder`1.Perform(IReadOnlyCollection`1 items, Int32 level, Group`1 parent)
   at Telerik.WinControls.Data.DataItemGroup`1.get_Groups()
   at Telerik.WinControls.UI.DataGroup.get_Groups()
   at Telerik.WinControls.UI.GridViewTemplate.InvalidateSummaryRowsCore(DataGroup group, Boolean invalidateChildren)
   at Telerik.WinControls.UI.GridViewTemplate.InvalidateSummaryRowsCore(DataGroup group, Boolean invalidateChildren)
   at Telerik.WinControls.UI.GridViewTemplate.InvalidateGroupSummaryRows(DataGroup group, Boolean invalidateChildren)
   at Telerik.WinControls.UI.GridViewTemplate.RefreshSummaryRowsInGroup(NotifyCollectionChangedEventArgs e)
   at Telerik.WinControls.UI.GridViewTemplate.RefreshAggregates(NotifyCollectionChangedEventArgs e)
   at Telerik.WinControls.UI.MasterGridViewTemplate.OnViewChanged(Object sender, DataViewChangedEventArgs e)
   at Telerik.WinControls.Data.RadDataView`1.RebuildData(Boolean notify)
   at Telerik.WinControls.Data.RadDataView`1.OnNotifyPropertyChanged(PropertyChangedEventArgs e)
   at Telerik.WinControls.Data.RadCollectionView`1.OnNotifyPropertyChanged(String propertyName)
   at Telerik.WinControls.UI.GridViewSortDescriptorCollection.OnCollectionChanged(NotifyCollectionChangedEventArgs args)
   at Telerik.WinControls.UI.GridViewSortDescriptorCollection.RemoveItem(Int32 index)
   at Telerik.WinControls.UI.GridViewColumn.Sort(RadSortOrder sortOrder, Boolean multiSortMode)
   at Telerik.WinControls.UI.GridHeaderCellElement.Sort(RadSortOrder sortOrder)
   at Telerik.WinControls.UI.GridHeaderRowBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.UI.BaseGridBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.UI.RadGridView.OnMouseUp(MouseEventArgs e)
   at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)
   at System.Windows.Forms.Control.WndProc(Message& m)
   at Telerik.WinControls.RadControl.WndProc(Message& m)
   at Telerik.WinControls.UI.RadGridView.WndProc(Message& m)
   at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

To reproduce, add menu item in the filtering context menu and upon click, set it as checked. Note that the filtering cell text should also take the custom menu item text or there should be an approach to set it.
Workaround: uncomment the commented code below.

protected override void OnLoad(EventArgs e)
        {
            base.OnLoad(e);

            AddGrid();

            DataTable dt = new DataTable();
            dt.Columns.Add("Id", typeof(int));
            dt.Columns.Add("Name", typeof(string));

            for (int i = 0; i < 5; i++)
            {
                dt.Rows.Add(i, "Item" + i);
            }
            dt.Rows.Add(5, null);
            dt.Rows.Add(6, "");

            radGridView1.ShowHeaderCellButtons = true;
            this.radGridView1.DataSource = dt;
            this.radGridView1.AutoSizeColumnsMode = Telerik.WinControls.UI.GridViewAutoSizeColumnsMode.Fill;
            this.radGridView1.EnableFiltering = true;
            this.radGridView1.EnableCustomFiltering = true;
            //radGridView1.ContextMenuOpening += radGridView1_ContextMenuOpening;
        }

        private void radGridView1_ContextMenuOpening(object sender, Telerik.WinControls.UI.ContextMenuOpeningEventArgs e)
        {
            GridFilterCellElement filterCell = e.ContextMenuProvider as GridFilterCellElement;
            GridViewDataColumn dataCol = (GridViewDataColumn)filterCell.ColumnInfo;
            if (filterCell != null)
            {
                if (filterCell.ColumnInfo.Name == "Name")
                {
                    RadMenuItem isNullMenuItem = new RadMenuItem();
                    isNullMenuItem.Click += customMenuItem_Click;
                    isNullMenuItem.Text = "My IsNull";
                    isNullMenuItem.Tag = filterCell.ColumnInfo.Name;
                    e.ContextMenu.Items.Add(isNullMenuItem);

                    RadMenuItem isNotNullMenuItem = new RadMenuItem();
                    isNotNullMenuItem.Click += customMenuItem_Click;
                    isNotNullMenuItem.Text = "My IsNotNull";
                    isNotNullMenuItem.Tag = filterCell.ColumnInfo.Name;
                    e.ContextMenu.Items.Add(isNotNullMenuItem);

                    bool isCustomFilter = (dataCol.FilterDescriptor != null &&
                        dataCol.FilterDescriptor is CompositeFilterDescriptor &&
                        dataCol.FilterDescriptor.Expression.Contains("NULL"));

                    foreach (RadMenuItem item in e.ContextMenu.Items)
                    {
                        if (item.Text == "Is null" || item.Text == "Is not null")
                        {
                            item.Visibility = Telerik.WinControls.ElementVisibility.Collapsed;
                        }
                        //if (isCustomFilter)
                        //{
                        //    item.IsChecked = false;
                        //}
                    }
                    //if (isCustomFilter)
                    //{
                    //    if (((CompositeFilterDescriptor)dataCol.FilterDescriptor).LogicalOperator == FilterLogicalOperator.And)
                    //    {
                    //        isNotNullMenuItem.IsChecked = true;
                    //    }
                    //    else
                    //    {
                    //        isNullMenuItem.IsChecked = true;
                    //    }
                    //}
                }
            }
        }

        private void customMenuItem_Click(object sender, EventArgs e)
        {
            RadMenuItem clickedItem = (RadMenuItem)sender;
            string columnName = clickedItem.Tag.ToString();
            radGridView1.Columns[columnName].FilterDescriptor = null;

            FilterOperator filterOperator = clickedItem.Text.Contains("Not") ? FilterOperator.IsNotEqualTo : FilterOperator.IsEqualTo;
            FilterLogicalOperator logicalOperator = clickedItem.Text.Contains("Not") ? FilterLogicalOperator.And : FilterLogicalOperator.Or;

            CompositeFilterDescriptor compositeFilter = new CompositeFilterDescriptor();
            compositeFilter.FilterDescriptors.Add(new FilterDescriptor(columnName, filterOperator, ""));
            compositeFilter.FilterDescriptors.Add(new FilterDescriptor(columnName, filterOperator, null));
            compositeFilter.LogicalOperator = logicalOperator;
            compositeFilter.IsFilterEditor = true;
            this.radGridView1.FilterDescriptors.Add(compositeFilter);

            clickedItem.IsChecked = true;
        }

Use attached to reproduce.

This is not an issue. Performing Begin/End update disposes of all elements along with the globally declared item. You need to check if the item is disposed of:
void ContextMenuOpening(object sender, ContextMenuOpeningEventArgs e)
{
    if (menuItem.IsDisposed)
    {
        menuItem = new RadMenuItem();
        menuItem.Text = "Custom menu item";
        menuItem.Click += menuItem_Click;
    }
    e.ContextMenu.Items.Add(menuItem);
}

To reproduce:
Public Class RadForm1
    Public RadGridView1 As RadGridView

    Private Sub RadForm1_Load(sender As Object, e As EventArgs) Handles Me.Load
        CreateGrid()
        FormatGrid()
        SetDataSource()
    End Sub

    Private Sub CreateGrid()
        Try
            RadGridView1 = New RadGridView
            Me.Controls.Add(RadGridView1)
        Catch ex As Exception
            MessageBox.Show(Me, ex.Message)
        End Try
    End Sub
    Private Sub FormatGrid()

        Dim col As GridViewTextBoxColumn
        With RadGridView1
            col = New GridViewTextBoxColumn
            With col
                .FieldName = "FieldID"
                'NOTE: Comment out NullValue = "" to prevent the unhandled exception
                .NullValue = ""
            End With
            .Columns.Add(col)
        End With
    End Sub
    Private Sub SetDataSource()
        Dim table As DataTable = Nothing
        Dim row As DataRow = Nothing
        table = New DataTable("GridList")
        table.Columns.Add("FieldID", GetType(System.Guid))
        row = table.NewRow
        row("FieldID") = Guid.Empty
        table.Rows.Add(row)
        RadGridView1.DataSource = table
    End Sub
End Class

Workaround:
Comment this line 
NullValue = ""

To reproduce: please refer to the attached gif file and sample project.

Workaround: when you set the DrawFill property to true, specify the BackColor to the desired one and reset for the rest of the cells.

private void radGridView1_CellFormatting(object sender, Telerik.WinControls.UI.CellFormattingEventArgs e)
{
    if (e.Column.Name == "ProductName" && e.Row is GridViewDataRowInfo)
    {
        if (e.CellElement.Value.ToString().Contains("C"))
        {
            e.CellElement.DrawFill = true;
            e.CellElement.BackColor = Color.Yellow;
            e.CellElement.GradientStyle = GradientStyles.Solid;
            e.CellElement.ForeColor = Color.OliveDrab;
        }
        else
        { 
            e.CellElement.ResetValue(LightVisualElement.DrawFillProperty, ValueResetFlags.Local);
            e.CellElement.ResetValue(LightVisualElement.GradientStyleProperty, ValueResetFlags.Local);
            e.CellElement.ResetValue(LightVisualElement.ForeColorProperty, ValueResetFlags.Local);  
            e.CellElement.ResetValue(LightVisualElement.BackColorProperty, ValueResetFlags.Local);  
        }
    }
    else
    { 
        e.CellElement.ResetValue(LightVisualElement.DrawFillProperty, ValueResetFlags.Local);
        e.CellElement.ResetValue(LightVisualElement.GradientStyleProperty, ValueResetFlags.Local);
        e.CellElement.ResetValue(LightVisualElement.ForeColorProperty, ValueResetFlags.Local);    
        e.CellElement.ResetValue(LightVisualElement.BackColorProperty, ValueResetFlags.Local);  
    }
}

To reproduce:
- Add a RadGridView and a button to a blank form.
- Subscribe to CellValidating event from the grid and set the cancel property of the CellValidatingEventArgs to true upon some condition.
- Add click event handler for the button and print a message in it.
- Start the application and enter some invalid data in the grid cell, then click the button.
- The code from the button's event handler is executed.

Workaround use a flag to determine when to execute the corresponding button code:
bool validating = false;

void radGridView1_CellValidating(object sender, Telerik.WinControls.UI.CellValidatingEventArgs e)
{
    if (e.Value.ToString().Length < 5)
    {
        e.Cancel = true;
        validating = true;
        e.Row.ErrorText = "Validation error!";
    }
    else
    {
        validating = false;
    }
}

private void radButton1_Click(object sender, EventArgs e)
{
    if (!validating)
    {
        Debug.WriteLine("Executed");
    }
}

Create a grid with more than 20 columns and add 5K rows for example. Maximize the form and try to scroll with mouse wheel. You will notice that the scrolling performance is worse compared to the normal state of the form with less visible visual elements.

Workaround: this.radGridView1.EnableFastScrolling = true; and use the scrollbar's thumb

Second workaround: use paging:  https://docs.telerik.com/devtools/winforms/gridview/paging/overview Thus, you will display as many rows as possible to display on the screen per page. Instead of scrolling, you will navigate through pages.

Hi Mostafa,

The end users can copy a single cell even when the SelectionMode is set to FullRowSelect via the ContextMenu when opening it on any of the data cells. If the context menu is opened on the row header they will select the whole row. Please check the attached video: radgridview-context-menu-behavior.gif.

If you would like to copy a single cell using the Ctrl-C command and have the grid setup in FullRowSelect mode please check the attached project featuring a solution. I am also attaching a video showing the result using the custom implementation in the project: radgridview-full-row-ctrl-c.gif

To reproduce
- Start the attached project press "Add in code"  then "Save"
- The row is still not added to the underlying data table. 

Workaround:
TryCast(Me.radGridView1.Rows.Last().DataBoundItem, IEditableObject).EndEdit()

To reproduce: please refer to the attached sample project and gif file illustrating the behavior.

Workaround: in order to cancel adding of the new row, you can call the MasterView.TableAddNewRow.CancelAddNewRow method:

private void radGridView1_UserAddingRow(object sender, Telerik.WinControls.UI.GridViewRowCancelEventArgs e)
{
    e.Cancel = true;
    this.radGridView1.MasterView.TableAddNewRow.CancelAddNewRow(); 
    int index = this.radGridView1.Rows.Count;
    this.radGridView1.Rows.Add(index, "Row" + index);
}

To reproduce: please refer to the attached sample project. 

Workaround:   this.radGridView1.TableElement.ScrollToRow(this.radGridView1.RowCount-1);

Steps to reproduce:

1. Add a CompositeFilterDescriptor programmatically as it is demonstrated in the following help article: http://docs.telerik.com/devtools/winforms/gridview/filtering/setting-filters-programmatically-(composite-descriptors)
2. Save the layout.
3. Load the layout.

Workaround: specify the PropertyName property for the CompositeFilterDescriptor.