How to reproduce: check the attached video
public partial class Form1 : Form
{
    public Form1()
    {
        InitializeComponent();
        
        this.radGridView1.DataSource = this.GetData(1000);
        this.radGridView1.AutoExpandGroups = true;
        this.radGridView1.EnableFiltering = true;
        this.radGridView1.EnablePaging = true;
        this.radGridView1.AutoSizeColumnsMode = GridViewAutoSizeColumnsMode.Fill;
    }

    private DataTable GetData(int count)
    {
        DataTable dt = new DataTable();
        dt.Columns.Add("Id", typeof(int));
        dt.Columns.Add("Name", typeof(string));
        dt.Columns.Add("Date", typeof(DateTime));
        dt.Columns.Add("Bool", typeof(bool));

        for (int i = 0; i < count; i++)
        {

            dt.Rows.Add(i,"Name " + i,  DateTime.Now.AddDays(i), i % 2 == 0 ? true : false);
        }

        return dt;
    }
}

Workaround: cancel the PageChanging event
public partial class Form1 : Form
{
    public Form1()
    {
        InitializeComponent();
        
        this.radGridView1.DataSource = this.GetData(1000);
        this.radGridView1.AutoExpandGroups = true;
        this.radGridView1.EnableFiltering = true;
        this.radGridView1.EnablePaging = true;
        this.radGridView1.AutoSizeColumnsMode = GridViewAutoSizeColumnsMode.Fill;

        timer = new Timer();
        timer.Interval = 100;
        timer.Tick += (sender, e) =>
        {
            timer.Stop();
            this.shouldCancel = false;
        };

        this.radGridView1.PageChanging += RadGridView1_PageChanging;
        this.radGridView1.CurrentRowChanged += RadGridView1_CurrentRowChanged;
    }

    private void RadGridView1_CurrentRowChanged(object sender, CurrentRowChangedEventArgs e)
    {
        this.shouldCancel = this.ShouldCancelPageChange(e.CurrentRow);
        timer.Start();
    }

    Timer timer;
    bool shouldCancel = false;

    private bool ShouldCancelPageChange(GridViewRowInfo rowInfo)
    {
        if (this.radGridView1.TableElement.MasterTemplate != null && this.radGridView1.TableElement.MasterTemplate.EnablePaging)
        {
            int pageIndex = this.radGridView1.TableElement.ViewTemplate.DataView.GetItemPage(rowInfo);

            if (pageIndex == this.radGridView1.TableElement.MasterTemplate.PageIndex)
            {
                return true;
            }
        }

        return false;
    }

    private void RadGridView1_PageChanging(object sender, Telerik.WinControls.PageChangingEventArgs e)
    {
        e.Cancel = this.shouldCancel;
    }

    private DataTable GetData(int count)
    {
        DataTable dt = new DataTable();
        dt.Columns.Add("Id", typeof(int));
        dt.Columns.Add("Name", typeof(string));
        dt.Columns.Add("Date", typeof(DateTime));
        dt.Columns.Add("Bool", typeof(bool));

        for (int i = 0; i < count; i++)
        {

            dt.Rows.Add(i,"Name " + i,  DateTime.Now.AddDays(i), i % 2 == 0 ? true : false);
        }

        return dt;
    }
}

I have a GridView (Winforms v. 2017.3.1017.40, same problem with 2017.2.502.40) configured as on the attached screenshot (made some groups, made a search, and used the "excel-like" filter on a column to uncheck some values).

Then I try to click on some column headers to sort the grid.
After a few clicks, I get this error :
InvalidOperationException: La collection a été modifiée ; l'opération d'énumération peut ne pas s'exécuter.

I got different stacktrace with the same error :
InvalidOperationException: La collection a été modifiée ; l'opération d'énumération peut ne pas s'exécuter.
   at System.ThrowHelper.ThrowInvalidOperationException(ExceptionResource resource)
   at System.Collections.Generic.List`1.Enumerator.MoveNextRare()
   at System.Collections.Generic.List`1.Enumerator.MoveNext()
   at Telerik.WinControls.UI.DataGroup.<GetEnumerator>d__0.MoveNext()
   at Telerik.WinControls.UI.GridViewGroupRowInfo.get_ChildRows()
   at Telerik.WinControls.UI.GridViewRowInfo.HasChildRows()
   at Telerik.WinControls.UI.PrintGridTraverser.CanStepInHierarchy()
   at Telerik.WinControls.UI.GridTraverser.StepInHierarchy()
   at Telerik.WinControls.UI.GridTraverser.MoveNextCore()
   at Telerik.WinControls.UI.GridTraverser.MoveNext()
   at Telerik.WinControls.UI.GridViewSearchRowInfo.worker_DoWork(Object sender, DoWorkEventArgs e)
   at System.ComponentModel.BackgroundWorker.OnDoWork(DoWorkEventArgs e)
   at System.ComponentModel.BackgroundWorker.WorkerThreadStart(Object argument)

-----

InvalidOperationException: Failed to compare two elements in the array. ---> NullReferenceException: Object reference not set to an instance of an object.
   at Telerik.WinControls.UI.GridViewRowInfoComparer.CompareRows(GridViewRowInfo x, GridViewRowInfo y, SortDescriptorCollection context)
   at System.Collections.Generic.ArraySortHelper`1.InternalBinarySearch(T[] array, Int32 index, Int32 length, T value, IComparer`1 comparer)
   at System.Collections.Generic.ArraySortHelper`1.BinarySearch(T[] array, Int32 index, Int32 length, T value, IComparer`1 comparer)


   --- End of inner exception stack trace ---
   at System.Collections.Generic.ArraySortHelper`1.BinarySearch(T[] array, Int32 index, Int32 length, T value, IComparer`1 comparer)
   at System.Collections.Generic.List`1.BinarySearch(Int32 index, Int32 count, T item, IComparer`1 comparer)
   at Telerik.Collections.Generic.HybridIndex`1.PerformWithQuickSort()
   at Telerik.Collections.Generic.HybridIndex`1.get_Items()
   at Telerik.Collections.Generic.Index`1.GetEnumerator()
   at Telerik.WinControls.Data.GroupBuilder`1.Perform(IReadOnlyCollection`1 items, Int32 level, Group`1 parent)
   at Telerik.WinControls.Data.GroupBuilder`1.get_Groups()
   at Telerik.WinControls.UI.GridViewInfo.Refresh()
   at Telerik.WinControls.UI.GridViewInfo.get_ChildRows()
   at Telerik.WinControls.UI.ViewInfoTraverser.SetCollectionForStage(Boolean initializeCollection)
   at Telerik.WinControls.UI.ViewInfoTraverser.ChangeCollectionForward()
   at Telerik.WinControls.UI.ViewInfoTraverser.MoveNextCore()
   at Telerik.WinControls.UI.ViewInfoTraverser.MoveNext()
   at Telerik.WinControls.UI.GridTraverser.MoveNextCore()
   at Telerik.WinControls.UI.GridTraverser.MoveNext()
   at Telerik.WinControls.UI.BaseGridNavigator.NavigateToRow(GridViewRowInfo row, Boolean select)
   at Telerik.WinControls.UI.BaseGridNavigator.ProcessViewChangedEvent(GridViewEvent eventData)
   at Telerik.WinControls.UI.BaseGridNavigator.ProcessEventCore(GridViewEvent eventData)
   at Telerik.WinControls.UI.GridViewEventProcessEntity.ProcessCollection(GridViewEvent gridEvent, PriorityWeakReferenceList list, GridEventProcessMode processMode)
   at Telerik.WinControls.UI.GridViewEventProcessEntity.ProcessEvent(GridViewEvent gridEvent)
   at Telerik.WinControls.UI.GridViewSynchronizationService.NotifyListeners(GridViewEvent gridEvent)
   at Telerik.WinControls.UI.GridViewSynchronizationService.FlushEvents()
   at Telerik.WinControls.UI.GridViewSynchronizationService.DispatchEvent(GridViewEvent gridEvent)
   at Telerik.WinControls.UI.GridViewSynchronizationService.DispatchEvent(GridViewTemplate template, GridViewEvent eventData, Boolean postUI)
   at Telerik.WinControls.UI.GridViewTemplate.DispatchDataViewChangedEvent(Object sender, DataViewChangedEventArgs args)
   at Telerik.WinControls.UI.GridViewTemplate.OnViewChanged(Object sender, DataViewChangedEventArgs e)
   at Telerik.WinControls.UI.MasterGridViewTemplate.OnViewChanged(Object sender, DataViewChangedEventArgs e)
   at Telerik.WinControls.Data.RadDataView`1.RebuildData(Boolean notify)
   at Telerik.WinControls.Data.RadDataView`1.OnNotifyPropertyChanged(PropertyChangedEventArgs e)
   at Telerik.WinControls.Data.RadCollectionView`1.OnNotifyPropertyChanged(String propertyName)
   at Telerik.WinControls.UI.GridViewSortDescriptorCollection.OnCollectionChanged(NotifyCollectionChangedEventArgs args)
   at System.ComponentModel.PropertyChangedEventHandler.Invoke(Object sender, PropertyChangedEventArgs e)
   at Telerik.WinControls.Data.SortDescriptor.set_Direction(ListSortDirection value)
   at Telerik.WinControls.UI.GridViewColumn.Sort(RadSortOrder sortOrder, Boolean multiSortMode)
   at Telerik.WinControls.UI.GridHeaderCellElement.Sort(RadSortOrder sortOrder)
   at Telerik.WinControls.UI.GridHeaderRowBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.UI.BaseGridBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.UI.RadGridView.OnMouseUp(MouseEventArgs e)
   at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)
   at System.Windows.Forms.Control.WndProc(Message& m)
   at Telerik.WinControls.RadControl.WndProc(Message& m)
   at Telerik.WinControls.UI.RadGridView.WndProc(Message& m)
   at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

------

InvalidOperationException: Collection was modified; enumeration operation may not execute.
   at System.ThrowHelper.ThrowInvalidOperationException(ExceptionResource resource)
   at System.Collections.Generic.List`1.Enumerator.MoveNextRare()
   at System.Collections.Generic.List`1.Enumerator.MoveNext()
   at Telerik.WinControls.UI.DataGroup.<GetEnumerator>d__0.MoveNext()
[...]
   at System.Collections.Generic.List`1..ctor(IEnumerable`1 collection)
   at System.Linq.Enumerable.ToList[TSource](IEnumerable`1 source)
   at Alto.Client.Controls.Dispatch.DispatchResources.DeliveryPointFilterManager.get_DeliveryPointsVisible() in d:\Builds\45153\Alto\Alto.Prod\src\Alto\Alto.Client\Controls\Dispatch\DispatchResources\DeliveryPointFilterManager.cs:line 38
   at Alto.Client.Controls.Dispatch.DispatchResources.UcDeliveryPoint.get_Title() in d:\Builds\45153\Alto\Alto.Prod\src\Alto\Alto.Client\Controls\Dispatch\DispatchResources\UcDeliveryPoint.cs:line 1520
   at Alto.Client.Controls.Dispatch.DispatchResources.UcDeliveryPoint.updatePanelTitle() in d:\Builds\45153\Alto\Alto.Prod\src\Alto\Alto.Client\Controls\Dispatch\DispatchResources\UcDeliveryPoint.cs:line 543
   at Alto.Client.Controls.Dispatch.DispatchResources.UcDeliveryPoint.onFilterChanged(Object sender, GridViewCollectionChangedEventArgs e) in d:\Builds\45153\Alto\Alto.Prod\src\Alto\Alto.Client\Controls\Dispatch\DispatchResources\UcDeliveryPoint.cs:line 547
   at Telerik.WinControls.UI.GridViewCollectionChangedEventHandler.Invoke(Object sender, GridViewCollectionChangedEventArgs e)
   at Telerik.WinControls.UI.RadGridView.OnFilterChanged(Object sender, GridViewCollectionChangedEventArgs e)
   at Telerik.WinControls.UI.EventDispatcher.RaiseEvent[T](Object eventKey, Object sender, T args)
   at Telerik.WinControls.UI.GridViewFilterDescriptorCollection.OnCollectionChanged(NotifyCollectionChangedEventArgs args)
   at Telerik.Collections.Generic.NotifyCollection`1.InsertItem(Int32 index, T item)
   at Telerik.WinControls.UI.GridViewFilterDescriptorCollection.InsertItem(Int32 index, FilterDescriptor item)
   at System.Collections.ObjectModel.Collection`1.Add(T item)
   at Telerik.WinControls.UI.GridViewDataColumn.SetFilterDescriptor(FilterDescriptor value)
   at Telerik.WinControls.UI.GridHeaderCellElement.filterPopup_FilterConfirmed(Object sender, EventArgs e)
   at Telerik.WinControls.UI.BaseFilterPopup.OnFilterConfirmed()
   at Telerik.WinControls.UI.RadListFilterPopup.OnButtonOkClick(EventArgs e)
   at Telerik.WinControls.UI.RadListFilterPopup.ButtonOK_Click(Object sender, EventArgs e)
   at Telerik.WinControls.RadElement.OnClick(EventArgs e)
   at Telerik.WinControls.UI.RadButtonItem.OnClick(EventArgs e)
   at Telerik.WinControls.UI.RadButtonElement.OnClick(EventArgs e)
   at Telerik.WinControls.RadElement.DoClick(EventArgs e)
   at Telerik.WinControls.RadElement.RaiseBubbleEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadItem.RaiseBubbleEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadElement.RaiseRoutedEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadElement.RaiseBubbleEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadItem.RaiseBubbleEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadElement.RaiseRoutedEvent(RadElement sender, RoutedEventArgs args)
   at Telerik.WinControls.RadElement.DoMouseUp(MouseEventArgs e)
   at Telerik.WinControls.ComponentInputBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.RadControl.OnMouseUp(MouseEventArgs e)
   at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)
   at System.Windows.Forms.Control.WndProc(Message& m)
   at System.Windows.Forms.ScrollableControl.WndProc(Message& m)
   at Telerik.WinControls.RadControl.WndProc(Message& m)
   at Telerik.WinControls.UI.RadPopupControlBase.WndProc(Message& m)
   at System.Windows.Forms.Control.ControlNativeWindow.OnMessage(Message& m)
   at System.Windows.Forms.Control.ControlNativeWindow.WndProc(Message& m)
   at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

----

InvalidOperationException: Collection was modified; enumeration operation may not execute.
   at System.Collections.Generic.List`1.Enumerator.MoveNextRare()
   at Telerik.WinControls.UI.DataGroup.<GetEnumerator>d__0.MoveNext()
   at Telerik.WinControls.Data.GroupBuilder`1.Perform(IReadOnlyCollection`1 items, Int32 level, Group`1 parent)
   at Telerik.WinControls.Data.DataItemGroup`1.get_Groups()
   at Telerik.WinControls.UI.DataGroup.get_Groups()
   at Telerik.WinControls.UI.GridViewTemplate.InvalidateSummaryRowsCore(DataGroup group, Boolean invalidateChildren)
   at Telerik.WinControls.UI.GridViewTemplate.InvalidateSummaryRowsCore(DataGroup group, Boolean invalidateChildren)
   at Telerik.WinControls.UI.GridViewTemplate.InvalidateGroupSummaryRows(DataGroup group, Boolean invalidateChildren)
   at Telerik.WinControls.UI.GridViewTemplate.RefreshSummaryRowsInGroup(NotifyCollectionChangedEventArgs e)
   at Telerik.WinControls.UI.GridViewTemplate.RefreshAggregates(NotifyCollectionChangedEventArgs e)
   at Telerik.WinControls.UI.MasterGridViewTemplate.OnViewChanged(Object sender, DataViewChangedEventArgs e)
   at Telerik.WinControls.Data.RadDataView`1.RebuildData(Boolean notify)
   at Telerik.WinControls.Data.RadDataView`1.OnNotifyPropertyChanged(PropertyChangedEventArgs e)
   at Telerik.WinControls.Data.RadCollectionView`1.OnNotifyPropertyChanged(String propertyName)
   at Telerik.WinControls.UI.GridViewSortDescriptorCollection.OnCollectionChanged(NotifyCollectionChangedEventArgs args)
   at Telerik.WinControls.UI.GridViewSortDescriptorCollection.RemoveItem(Int32 index)
   at Telerik.WinControls.UI.GridViewColumn.Sort(RadSortOrder sortOrder, Boolean multiSortMode)
   at Telerik.WinControls.UI.GridHeaderCellElement.Sort(RadSortOrder sortOrder)
   at Telerik.WinControls.UI.GridHeaderRowBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.UI.BaseGridBehavior.OnMouseUp(MouseEventArgs e)
   at Telerik.WinControls.UI.RadGridView.OnMouseUp(MouseEventArgs e)
   at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)
   at System.Windows.Forms.Control.WndProc(Message& m)
   at Telerik.WinControls.RadControl.WndProc(Message& m)
   at Telerik.WinControls.UI.RadGridView.WndProc(Message& m)
   at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

To reproduce: please refer to the attached gif file and sample project.

Workaround:

        private void radGridView1_CellEndEdit(object sender, GridViewCellEventArgs e)
        {
            RadDropDownListEditor editor = e.ActiveEditor as RadDropDownListEditor;
            if (editor!=null)
            {
                RadDropDownListEditorElement el = editor.EditorElement as RadDropDownListEditorElement;
                el.AutoCompleteSuggest.DropDownList.ClosePopup();
            } 
        }

To reproduce:

   Sub New()
         
        InitializeComponent()
        Dim dt As New DataTable
        dt.Columns.Add("Id", GetType(Integer))
        dt.Columns.Add("Name", GetType(String))
        For index = 1 To 1000
            dt.Rows.Add(index, "Item" & index)
        Next
        Me.RadGridView1.DataSource = dt


    End Sub
    Private Sub RadButton1_Click(sender As Object, e As EventArgs) Handles RadButton1.Click
        Dim pdfFile As String = "..\..\exportedFile.pdf"
        Dim pdfExporter As New GridViewPdfExport(Me.RadGridView1)
        pdfExporter.ShowHeaderAndFooter = True
        pdfExporter.FitToPageWidth = True
        AddHandler pdfExporter.PdfExported, AddressOf pdfExporter_PdfExported
        Dim renderer As New PdfExportRenderer()
        pdfExporter.RunExport(pdfFile, renderer)

        Process.Start(pdfFile)
    End Sub

    Private Sub pdfExporter_PdfExported(sender As Object, e As System.EventArgs)

        Dim pdfFile As String = "..\..\exportedFile.pdf"
        Dim document As RadFixedDocument
        Dim provider As Telerik.Windows.Documents.Fixed.FormatProviders.Pdf.PdfFormatProvider = New Telerik.Windows.Documents.Fixed.FormatProviders.Pdf.PdfFormatProvider()
        Using stream As Stream = File.OpenRead(pdfFile)
            document = provider.Import(stream)  '<==== Error Found
            For Each page As RadFixedPage In document.Pages
                Dim editor As FixedContentEditor = New FixedContentEditor(page)
                editor.Position.Translate(page.Size.Width / 2, page.Size.Height - 50)

                Dim pageNum As Integer = document.Pages.IndexOf(page) + 1
                editor.DrawText(pageNum + " of " + document.Pages.Count)
            Next
        End Using

        Using output As Stream = File.OpenWrite(pdfFile)
            provider.Export(document, output)    '<==== Error Found
        End Using

        Process.Start(pdfFile)
    End Sub

Workaround: use the PdfExportRenderer.PdfExporting event where you have access to the document and you can make any customizations to it:
        Dim pdfFile As String = "..\..\exportedFile.pdf"
        Dim pdfExporter As New GridViewPdfExport(Me.RadGridView1)
        pdfExporter.ShowHeaderAndFooter = True
        pdfExporter.FitToPageWidth = True
        Dim renderer As New PdfExportRenderer()
        AddHandler renderer.PdfExporting, AddressOf PdfExporting
        pdfExporter.RunExport(pdfFile, renderer)

    Private Sub PdfExporting(sender As Object, e As PdfExportingEventArgs)
        Dim document As RadFixedDocument = e.Document
        Dim provider As Telerik.Windows.Documents.Fixed.FormatProviders.Pdf.PdfFormatProvider = New Telerik.Windows.Documents.Fixed.FormatProviders.Pdf.PdfFormatProvider()

        For Each page As RadFixedPage In document.Pages
            Dim editor As FixedContentEditor = New FixedContentEditor(page)
            editor.Position.Translate(page.Size.Width / 2, page.Size.Height - 50)

            Dim pageNum As Integer = document.Pages.IndexOf(page) + 1
            editor.DrawText(pageNum & " of " & document.Pages.Count)
        Next 
    End Sub

To reproduce: run the project, select the grid and press Tab. You will notice a message box for the first grid which won't be shown for the second in the popup.

Use attached to reproduce.

Workaround:
class MyGridCheckBoxHeaderCellElement : GridCheckBoxHeaderCellElement
{
    public MyGridCheckBoxHeaderCellElement(GridRowElement row, GridViewColumn col) : base(col, row)
    {
    }
    bool suspenUpdate = false;
    protected override void checkbox_ToggleStateChanged(object sender, StateChangedEventArgs args)
    {
        suspenUpdate = true;
        base.checkbox_ToggleStateChanged(sender, args);
        suspenUpdate = false;
    }
    protected override void SetCheckBoxState()
    {
        if (!suspenUpdate)
        {
            base.SetCheckBoxState();
        }
        
    }
}

private void RadGridView1_CreateCell(object sender, GridViewCreateCellEventArgs e)
{
    if (e.Column != null&& e.CellType == typeof(GridCheckBoxHeaderCellElement))
    {
        e.CellElement = new MyGridCheckBoxHeaderCellElement(e.Row, e.Column);
    }
}

In self-reference if you bind the grid to a record having is ParentId the same as its Id, the grid will try to create a row which is parented by itself. This is not valid input data and we should throw a proper exception, otherwise the application will freeze.

How to reproduce: 
public partial class Form2 : Form
{
    private BindingList<DataObject> data;

    public Form2()
    {
        InitializeComponent();

        this.radGridView1.AutoGenerateHierarchy = true;
        this.data = new BindingList<DataObject>();

        int count = 10;
        for (int i = 0; i < count; i++)
        {
            DataObject p = new DataObject();
            p.Id = i;
            p.Name = "Parent " + i;
            this.data.Add(p);

            for (int j = 0; j < count; j++)
            {
                DataObject c = new DataObject();
                c.Id = count + j + i * count;
                c.Name = "Child " + i;
                c.ParentId = i;
                this.data.Add(c);
            }
        }

        this.radButton1.Click += RadButton1_Click;
    }

    private void RadButton1_Click(object sender, EventArgs e)
    {
        if (this.radGridView1.Relations.Count > 0)
        {
            this.radGridView1.Relations.Clear();
        }

        this.radGridView1.DataSource = this.data;
        this.radGridView1.Relations.AddSelfReference(this.radGridView1.MasterTemplate, "Id", "ParentId");

    }
}

public class DataObject
{
    public int Id { get; set; }

    public string Name { get; set; }

    public int ParentId { get; set; }
}


Workaround: set the ParentId of the parent records

int count = 10;
for (int i = 0; i < count; i++)
{
    DataObject p = new DataObject();
    p.Id = i;
    p.Name = "Parent " + i;
    p.ParentId = -1;
    this.data.Add(p);

    for (int j = 0; j < count; j++)
    {
        DataObject c = new DataObject();
        c.Id = count + j + i * count;
        c.Name = "Child " + i;
        c.ParentId = i;
        this.data.Add(c);
    }
}

How to reproduce: check the code snippet below and the attached video. 
public partial class Form1 : Form
{
    public Form1()
    {
        InitializeComponent();
        this.SetupGrid();

        this.radGridView1.Dock = DockStyle.Fill;
        this.radGridView1.UseScrollbarsInHierarchy = true;
    }

    private void SetupGrid()
    {
        BindingList<Teacher> teachers = new BindingList<Teacher>();
        BindingList<Student> students = new BindingList<Student>();

        for (int i = 1; i <= 2; i++)
        {
            teachers.Add(new Teacher
            {
                TeacherId = i,
                TeacherFirstName = "FirstName " + i,
                TeacherLastName = "FirstName " + i,

            });

            for (int j = 1; j <= 3; j++)
            {
                students.Add(new Student
                {
                    SudentId = j,
                    TeacherId = i,
                    SudentFirstName = "Student " + j,
                    SudentLastName = "LastName " + j,

                });
            }
        }

        this.radGridView1.Templates.Clear();
        this.radGridView1.DataSource = null;

        this.radGridView1.DataSource = teachers;
        this.radGridView1.AutoSizeColumnsMode = GridViewAutoSizeColumnsMode.Fill;

        GridViewTemplate template = new GridViewTemplate();
        template.AutoSizeColumnsMode = GridViewAutoSizeColumnsMode.Fill;
        template.DataSource = students;
        this.radGridView1.MasterTemplate.Templates.Add(template);

        GridViewRelation relation = new GridViewRelation(radGridView1.MasterTemplate);
        relation.ChildTemplate = template;
        relation.RelationName = "TeacherStudents";
        relation.ParentColumnNames.Add("TeacherId");
        relation.ChildColumnNames.Add("TeacherId");
        this.radGridView1.Relations.Add(relation);

        this.radGridView1.ChildViewExpanded += RadGridView1_ChildViewExpanded1;
    }

    private void RadGridView1_ChildViewExpanded1(object sender, ChildViewExpandedEventArgs e)
    {
    }

    private void radButton1_Click(object sender, EventArgs e)
    {
        this.radGridView1.SaveLayout("..\\..\\save.xml");
    }

    private void radButton2_Click(object sender, EventArgs e)
    {
        this.radGridView1.LoadLayout("..\\..\\save.xml");
    }
}

public class Teacher
{
    public int TeacherId { get; set; }

    public string TeacherFirstName { get; set; }

    public string TeacherLastName { get; set; }
}

public class Student
{
    public int SudentId { get; set; }

    public int TeacherId { get; set; }

    public string SudentFirstName { get; set; }

    public string SudentLastName { get; set; }
}


Workaround: prevent the child templates from serializing
public class MyRadGridView : RadGridView
{
    public override string ThemeClassName
    {
        get
        {
            return typeof(RadGridView).FullName;
        }
    }

    public override void SaveLayout(string fileName)
    {
        MyGridViewLayoutSerializer ser = new MyGridViewLayoutSerializer(this.XmlSerializationInfo);
        using (XmlTextWriter writer = new XmlTextWriter(fileName, Encoding.UTF8))
        {
            writer.Formatting = Formatting.Indented;
            writer.WriteStartElement("RadGridView");
            ser.WriteObjectElement(writer, this);
        }
    }
}

public class MyGridViewLayoutSerializer : GridViewLayoutSerializer
{
    public MyGridViewLayoutSerializer(ComponentXmlSerializationInfo componentSerializationInfo)
        : base(componentSerializationInfo)
    { }

    protected override bool ShouldSerializeValue(object component, PropertyDescriptor property, PropertySerializationMetadata overwriteMetadata)
    {
        if (property.Name == "Templates")
        {
            return false;
        }

        return base.ShouldSerializeValue(component, property, overwriteMetadata);
    }
}

To reproduce: please refer to the attached gif file and sample project

Workaround: set the AutoSizeRows property to false

The scenario which should be covered is selecting some data from Excel and pasting in the new row of RadGridView. This is an easy way for inserting data in the grid.

How to reproduce:
public partial class Form1 : Form
{
    public Form1()
    {
        InitializeComponent();

        this.radGridView1.DataSource = this.GetData();
        this.radGridView1.EditorRequired += RadGridView1_EditorRequired;
    }

    private void RadGridView1_EditorRequired(object sender, EditorRequiredEventArgs e)
    {
        if (this.radGridView1.CurrentColumn.Index == 0)
        {
            e.Editor = new RadTimePickerElement();
        }
    }

    private DataTable GetData()
    {
        DataTable dt = new DataTable();
        dt.Columns.Add("Date", typeof(DateTime));

        for (int i = 0; i < 20; i++)
        {
            DataRow r = dt.NewRow();
            dt.Rows.Add(r);
        }
        
        return dt;
    }
}

Workaround: the scenario is not completely valid as when handling the EditorRequiredEvent one should use the GridTimePickerEditor
1. Use the column`s EditorType property: 
((GridViewDateTimeColumn)this.radGridView1.Columns["Date"]).EditorType = GridViewDateTimeEditorType.TimePicker
2. Alternatively, handle the event this way:
private void RadGridView1_EditorRequired(object sender, EditorRequiredEventArgs e)
{
    if (this.radGridView1.CurrentColumn.Index == 0)
    {
        e.Editor = new GridTimePickerEditor();
    }
}

Use attached to reproduce.
- Check the filter box
- Uncheck the header checkbox.
- The cells are still visible and you cannot click on the data check boxes.

 

Use attached to reproduce.

Workaround:
class MyDataCellElement : GridDataCellElement
{
    public MyDataCellElement(GridViewColumn col, GridRowElement row) : base(col,row)
    { }

    protected override List<CharacterRange> GetSearchHighlightRanges()
    {
        // return base.GetSearchHighlightRanges();
        List<CharacterRange> ranges = new List<CharacterRange>();

        if (this.ColumnInfo == null || !this.RowInfo.SearchCache.Contains(this.ColumnInfo))
        {
            return ranges;
        }

        string criteria = this.RowInfo.SearchCache[this.ColumnInfo] as string;

        int index = -1;


        CompareOptions options;

        if (this.MasterTemplate.MasterViewInfo.TableSearchRow.CaseSensitive)
        {
            options = CompareOptions.Ordinal;
        }
        else
        {
            options = this.MasterTemplate.MasterViewInfo.TableSearchRow.CompareOptions;
        }

        do
        {
            if (index + 1 >= this.Text.Length)
            {
                break;
            }

            index = this.MasterTemplate.MasterViewInfo.TableSearchRow.Culture.CompareInfo.IndexOf(this.Text, criteria, index + 1, options);

            if (index >= 0)
            {
                var str = this.Text.Substring(index, criteria.Length);
                 
                int symbolCount = 0;
                foreach (char ch in str)
                {
                    if (!Char.IsLetterOrDigit(ch))
                    {
                        symbolCount++;
                    }
                }

                ranges.Add(new CharacterRange(index, criteria.Length + symbolCount));
            }

        } while (index >= 0 && ranges.Count < 32);

        return ranges;
    }
}

private void MasterTemplate_CreateCell(object sender, GridViewCreateCellEventArgs e)
{
    if (e.CellType == typeof(GridDataCellElement))
    {
        e.CellElement = new MyDataCellElement(e.Column, e.Row);
    }
   
}

To reproduce: run the attached sample project and click the new row.

Workaround: don't call the Begin/EndUpdate methods in the CurrentRowChanged event.

This new API will be useful for implementing custom sorting scenarios when you need to have custom sorting only for a single column.

A similar API is available for the filtering functionality (MasterTemplate.DataView.FilterEvaluate)

Use attached to reproduce.

This is not an issue. Performing Begin/End update disposes of all elements along with the globally declared item. You need to check if the item is disposed of:
void ContextMenuOpening(object sender, ContextMenuOpeningEventArgs e)
{
    if (menuItem.IsDisposed)
    {
        menuItem = new RadMenuItem();
        menuItem.Text = "Custom menu item";
        menuItem.Click += menuItem_Click;
    }
    e.ContextMenu.Items.Add(menuItem);
}

To reproduce:
- Add 7-8 columns to the grid.
- Set the AutoSizeColumnsMode to Fill
- Set the MaxWidth/MaxWidth of the last two columns.
- Resize the first column.
- Sometimes the size of the other columns is randomly increased/decreased.