To reproduce: please run the sample project and follow the steps from the gif file. You will notice that the clicks you perform, the much memory is consumed which is not released.

currently the chart is updated on MouseUp

If a RadChartView is set as the associated object of a RadRangeSelector and then is data bound the range selector does not render the chart in its inner element.

How to reproduce:
public partial class Form2 : Form
    {
        public Form2()
        {
            InitializeComponent();

            this.radRangeSelector1.AssociatedControl = this.radChartView1;
        }

        BindingList<MyCustomObject> myList;
        protected override void OnLoad(EventArgs e)
        {
            base.OnLoad(e);

            myList = new BindingList<MyCustomObject>();
            myList = new BindingList<MyCustomObject>();
            myList.Add(new MyCustomObject(1, "Outdoor"));
            myList.Add(new MyCustomObject(8, "Hardware"));
            myList.Add(new MyCustomObject(3, "Tools"));
            myList.Add(new MyCustomObject(6, "Books"));
            myList.Add(new MyCustomObject(2, "Appliances"));
            BarSeries barSeria = new BarSeries();
            radChartView1.Series.Add(barSeria);
            barSeria.DataSource = myList;
            barSeria.ValueMember = "MyInt";
            barSeria.CategoryMember = "MyString";
        }

        public class MyCustomObject : INotifyPropertyChanged
        {
            private int _myInt;
            private string _myString;
            public MyCustomObject(int myInt, string myString)
            {
                _myInt = myInt;
                _myString = myString;
            }
            public int MyInt
            {
                get { return _myInt; }
                set
                {
                    _myInt = value;
                    OnPropertyChanged("MyInt");
                }
            }
            public string MyString
            {
                get { return _myString; }
                set
                {
                    _myString = value;
                    OnPropertyChanged("MyString");
                }
            }
            public event PropertyChangedEventHandler PropertyChanged;
            protected virtual void OnPropertyChanged(string propertyName)
            {
                if (PropertyChanged != null)
                {
                    PropertyChanged(this, new PropertyChangedEventArgs(propertyName));
                }
            }
        }
    }

Workaround: 

Set the AssociatedControl property of the range selector after binding  the chart
public partial class Form2 : Form
    {
        public Form2()
        {
            InitializeComponent();
        }

        BindingList<MyCustomObject> myList;
        protected override void OnLoad(EventArgs e)
        {
            base.OnLoad(e);

            myList = new BindingList<MyCustomObject>();
            myList = new BindingList<MyCustomObject>();
            myList.Add(new MyCustomObject(1, "Outdoor"));
            myList.Add(new MyCustomObject(8, "Hardware"));
            myList.Add(new MyCustomObject(3, "Tools"));
            myList.Add(new MyCustomObject(6, "Books"));
            myList.Add(new MyCustomObject(2, "Appliances"));
            BarSeries barSeria = new BarSeries();
            radChartView1.Series.Add(barSeria);
            barSeria.DataSource = myList;
            barSeria.ValueMember = "MyInt";
            barSeria.CategoryMember = "MyString";

            this.radRangeSelector1.AssociatedControl = this.radChartView1;
        }

        public class MyCustomObject : INotifyPropertyChanged
        {
            private int _myInt;
            private string _myString;
            public MyCustomObject(int myInt, string myString)
            {
                _myInt = myInt;
                _myString = myString;
            }
            public int MyInt
            {
                get { return _myInt; }
                set
                {
                    _myInt = value;
                    OnPropertyChanged("MyInt");
                }
            }
            public string MyString
            {
                get { return _myString; }
                set
                {
                    _myString = value;
                    OnPropertyChanged("MyString");
                }
            }
            public event PropertyChangedEventHandler PropertyChanged;
            protected virtual void OnPropertyChanged(string propertyName)
            {
                if (PropertyChanged != null)
                {
                    PropertyChanged(this, new PropertyChangedEventArgs(propertyName));
                }
            }
        }
    }

To reproduce:

Add a RadChartView and add some data. Add a RadRangeSelector and set the AssociatedControl to be the chart.  On a button click set the Start and EndRange of the range selector. You will see in the chart that the range will not update.

Workaround:

Update the view manually:

this.rangeSelector.StartRange = 30;
this.rangeSelector.EndRange = 60;
(this.rangeSelector.RangeSelectorElement.AssociatedElement as IRangeSelectorElement).UpdateAssociatedView();