Bold/Italic does not work for some font styles.
This might be a framework limitation in WPF: https://www.telerik.com/forums/some-fonts-are-not-able-to-bold-italic
Sample fonts list:
Currently, the only customization that can be performed is using HyperlinkToolTipFormatString property of RadRichTextBox, which sets the format for all hyperlinks in the document of the control. It would be nice if it were possible to be able to set different tooltips.
Implement child dialogs for Style Formatting Properties Dialog. This will allow users to modify Style's properties related to font properties, paragraph properties, tabs, numbering and borders.

To reproduce set he following properties:
MouseSelectionHandler.DoubleClickTime = 1000;
MouseSelectionHandler.MouseDragThreshold = 2;
MouseSelectionHandler.MouseDoubleClickThreshold = 60;
Profiling results show bottleneck in the line-breaking logic within Paragraph MeasureOverride.