<TelerikDropDownList Data="@Products"
                     TItem="@Product"                     
                     TValue="@(int?)"
                     Value="@SelectedProductId"
                     ValueField="@nameof(Product.Id)"
                     TextField="@nameof(Product.Name)"
                     DefaultText="Select Product..."
                     ValueChanged="@( (int? newValue) => SelectedProductChanged(newValue) )"
                     Width="200px">
    <DropDownListSettings>
        <DropDownListPopupSettings Class="disabled-items" />
    </DropDownListSettings>
    <ItemTemplate>
        @{ var p = context as Product; }
        <div class="item-div @( !p.Active ? "disabled" : "" )"
             @onclick:preventDefault="@(!p.Active)"
             @onclick:stopPropagation="@(!p.Active)">
            @p.Name
        </div>
    </ItemTemplate>
</TelerikDropDownList>

<style>
    /* remove default item padding to prevent selection outside the template div */
    .disabled-items .k-list-item {
        padding: 0;
    }
    /* add back inner padding */
    .disabled-items .item-div {
        padding: 4px 8px;
    }
    /* style disabled items */
    .disabled-items .disabled {
        cursor: not-allowed;
        width: 100%;
        color: #ccc;
    }
</style>

@code {
    private List<Product> Products { get; set; }

    private int? SelectedProductId { get; set; }

    private async Task SelectedProductChanged(int? newValue)
    {
        var newProduct = Products.FirstOrDefault(x => x.Id == newValue);

        if (newProduct?.Active == true || !newValue.HasValue)
        {
            // select only active items or DefaultText
            SelectedProductId = newValue;
        }
        else
        {
            // skip disabled items during keyboard navigation
            var oldProductIndex = Products.FindIndex(x => x.Id == SelectedProductId);
            var newProductIndex = Products.FindIndex(x => x.Id == newValue);

            if (newProductIndex > oldProductIndex)
            {
                // skip forward
                SelectedProductId = Products[++newProductIndex].Id;
            }
            else
            {
                // skip backward
                SelectedProductId = Products[--newProductIndex].Id;
            }
        }
    }

    protected override void OnInitialized()
    {
        Products = new List<Product>();

        for (int i = 1; i <= 7; i++)
        {
            var active = i % 3 != 0;

            Products.Add(new Product()
            {
                Id = i,
                Name = (active ? "" : "Disabled ") + "Product " + i,
                Active = active
            });
        }

        base.OnInitialized();
    }

    public class Product
    {
        public int Id { get; set; }
        public string Name { get; set; }
        public bool Active { get; set; }
    }
}

	<select @onchange="@OnChangedAsync">
		<option></option>
		@if (DataSource != null)
		{
			@foreach (var item in DataSource)
			{
				<option @key="item" value="@optionValueFunc(item)" selected="@(item.Equals(SelectedItem))">@optionTextFunc(item)</option>
			}
		}
	</select>

	#region Private Members

	private Func<TSource, object> optionTextFunc;
	private Func<TSource, object> optionValueFunc;
	private TSource selectedItem = default(TSource);

	#endregion

        #region Public Parameters

	/// <summary>
	/// A List of objects to bind against.
	/// </summary>
	[Parameter]
	public IList<TSource> DataSource { get; set; } = new List<TSource>();

	/// <summary>
        /// A lambda expression referencing the property containing the text to display to the end user. Example: @(c => c.DisplayName)
        /// </summary>
        [Parameter]
        public Expression<Func<TSource, object>> OptionText { get; set; }

	/// <summary>
        /// A lambda expression referencing the property containing the value for this object, usually an identifier. Example: @(c => c.Id)
        /// </summary>
        [Parameter]
        public Expression<Func<TSource, object>> OptionValue { get; set; }

	/// <summary>
        /// The item from the <see cref="DataSource" /> that has been selected.
        /// </summary>
        [Parameter]
        public TSource SelectedItem { get; set; }

	/// <summary>
	/// The callback event required for two-way binding.
	/// </summary>
	[Parameter]
        public EventCallback<TSource> SelectedItemChanged { get; set; }

        #endregion

	private async Task OnChangedAsync(ChangeEventArgs changeEventArgs)
        {
            await UpdateSelection(DataSource.FirstOrDefault(c => optionValueFunc(c).ToString() == changeEventArgs.Value.ToString()));
        }

	private async Task UpdateSelection(TSource item)
        {
            selectedItem = item;
            await SelectedItemChanged.InvokeAsync(selectedItem);
        }

	protected override async Task OnInitializedAsync()
	{
            if (optionTextFunc == null && OptionText != null)
            {
                optionTextFunc = OptionText.Compile();
            }
            if (optionValueFunc == null && OptionText != null)
            {
                optionValueFunc = OptionValue.Compile();
            }
            await Task.CompletedTask;          
        }

<TelerikDropDownList Data="@MyList" bind-Value=@MyItem>

</TelerikDropDownList>
 
@functions {
    protected List<string> MyList = new List<string>() { "a", "b", "c" };
 
    protected string MyItem { get; set; } = "b";
}