DECLINED: This issue is not reproducible with R2 SP1 2016 Release.
A System.Windows.Documents.Hyperlink' is not a Visual or Visual3D Exception is thrown when you click on a Hyperlink inside a RadTabControl and then try to scroll using the MouseWheel Available in LIB version: 2014.3.1409
When pressing the Alt key, the access key of a given element must be displayed. Inside the Header of a TabItem it is not. The issue is not reproducible with the standard MS TabItem. It seems that it is related to the Foreground binding of the control. There is a workaround as shown below.
<telerik:RadTabControl>
<telerik:RadTabItem >
<telerik:RadTabItem.Header>
<AccessText Text="_Tab 1"
Foreground="{Binding RelativeSource={RelativeSource AncestorType=telerik:RadTabItem},
Path=Foreground}"/>
</telerik:RadTabItem.Header>
</telerik:RadTabItem>
</telerik:RadTabControl>
private void RadTabItem_PreviewMouseDown(object sender, MouseButtonEventArgs e) { if (e.ChangedButton == MouseButton.Middle) { e.Handled = true; } }