I suggest adding a FieldExpression property to the GridColumn so a developer would not need to create view models and templates for simple transformations of the existing model's properties. The field expression would be used for filtering and sorting as well. Its type would be Func<T, object> or Expression<Func<T, object>>.

   <TelerikGrid Data="@Persons">
            <GridColumns>
                <GridColumn FieldExpression="@(p => p.FirstName + " " + p.LastName)" />
            </GridColumns>
        </TelerikGrid>

   So what I propose is a fixed width for a column of the grid (and locked) with the remaining columns auto-sizing.

In my situation, I have an action switch button where the client can delete a row, edit a row etc but the action code dropdown column needs to ALWAYS be the same width.  The rest of the columns should automatically size based on the existing behaviour.

   Now I have tried using the autosize for just that column, but I have to render the grid first, then run the autosize (which gives a fun show of resizing to the user) then all the columns become fixed width, but the vertical scroll bar doesn't move and stays in its initial position.