Using the code code below, the RadBusyIndicator will animate the first time you toggle IsBusy.

However, any subsequent changes to IsBusy will show the AnimationType's graphic, but without animation.

<telerikBusyIndicator:RadBusyIndicator x:Name="radBusyIndicator"
                                               AnimationType="Animation4"
                                               IsBusy="{Binding IsBusy}"
                                               IsVisible="{Binding IsBusy}"
                                               Grid.RowSpan="3" />

The text can be used to show why the application is busy.

Available in the R2 2018 release.